Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is a Vietnamese traditionally medicinal plant employed in the treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. These studies aimed to look into the consequences of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcome indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the highest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (with the exception of total flavonoids) and antioxidant capacity, in comparison with conventional and ultrasound-assisted extractions. These data reveal that the application of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application from the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly modify the phytochemical compounds and biological activity from plant materials. The aims of this study would determine the results of drying methods, various solvents and extraction methods for the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root from Vietnam. The final results established that microwave drying was a highly effective method in removal of water regarding shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity in the P. trimera root while methanol and microwave-assisted extraction were the top solvent and way for greatest extraction of the phytochemical compounds and antioxidant capacity from the P. trimera root. The findings using this study allow retaining the greatest amounts of phytochemical compounds and antioxidant capacity from your P. trimera root for potential application in the nutraceutical industry.

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